The CD63-BCAR4 fusion gene discovered in Korean patients with lung adenocarcinoma consists of exons 1-3 of CD63 and exon 4 of BCAR4. Ectopic expression of the CD63-BCAR4 protein in normal bronchial epithelial cells resulted in enhanced cell proliferation and migration compared to that in control cells. This evidence concerns the gene CD63 and lung adenocarcinoma.