Not only that, Zhuang et al. and Song et al. have confirmed that CDKN2B-AS1 has been found to be an independent prognostic factor for LC and promotes the growth of LC cells through let-7c-5p/NAP1L1 axis [16, 17], thus showing the importance of CDKN2B-AS1 for LC. Here, NAP1L1 is linked to laryngotracheoesophageal cleft.