As a result, only the mRNA expression of CYB5R2, MME, and SERPINA9 was correlated with OS (P = 0.037, P = 0.001, and P = 0.037, respectively), whereas that of CYB5R2 and MME were correlated with PFS (P = 0.042 and P = 0.003, respectively) of CD5+ DLBCL. Here, CD5 is linked to diffuse large B-cell lymphoma.