Compared with CD5- DLBCL, CD5+ DLBCL showed higher expression of LIMD1 (LIM domain containing 1) and CCDC50 (coiled-coil domain containing 50) and lower expression of SERPINA9 (Serpin family A member 9), MAML3 (Mastermind like transcriptional coactivator 3), ITPKB (Inositol-trisphosphate 3-kinase B), and S1PR2 (Sphingosine-1-phosphate receptor 2) (Figure 5). The gene discussed is CD5; the disease is diffuse large B-cell lymphoma.