The infiltration level of CD4+ memory T cells activated, Macrophages M1, T cells follicular helper, CD8+ T cells, T cells regulatory, NK cells resting, and Dendritic cells activated had strongly positive correlations with TR-DDR score in at least five cancers, whereas the infiltration of CD4+ memory T cells resting, Macrophages M2, Mast cells resting, and Monocytes had negative correlations with TR-DDR score across in over five cancer types (Figure 5C). This evidence concerns the gene CD8A and cancer.