The infiltration of effector Th cells (OX40+) in cancer tissue with INFa tended to be more than that in INFc (INFa vs. INFc: 6.304 ± 2.615 vs. 5.220 ± 3.519, P = 0.083), but there was no significant difference in its distribution between INFa and INFb. This evidence concerns the gene TNFRSF4 and cancer.