revealed that an AA-sequence motif (PGLAG) was conserved in the TCR-ß CDR3 of Tax11-19–specific CD8+ T-cells among HLA-A*02:01+ HAM patients and expanded HTLV-1 Tax11-19–specific CD8+ T-cell clones in PB were also enriched in the CSF of the same patient by NGS-based TCR repertoire analysis technology (37). Here, CD8A is linked to tropical spastic paraparesis.