It was found that combining the DC growth factor FMS-like tyrosine kinase 3 ligand (Flt3L) secreted by T cells with the immune agonist poly (I:C) and anti-4-1BB, Flt3L-secreting T cells were found to increase the number of DCs within the tumor and significantly enhance T cell activity. Here, FLT3LG is linked to neoplasm.