For mice that were treated with EGb 761 orally following indomethacin-induced ulcerations, the levels of TNF-α (173.7 ± 10.98 pg/mL, p < 0.001) and the levels of IL-6 (188.8 ± 21.71 ng/L, p < 0.01) were considerably lowered (Figure 3) as compared to the ulcer group. This evidence concerns the gene IL6 and ulcer disease.