When compared to the ulcer group, prophylactic treatment with EGb 761 attenuated the elevation of the gastric tissue cytokines; TNF-α (178.3 ± 9.72 pg/mL, p < 0.001) and IL-6 (230 ± 13.73 ng/L, p < 0.001). Here, IL6 is linked to ulcer disease.