CCND1 and posterior cortical atrophy: The mechanism is that Tanshinone can significantly reduce cyclinD1, A, and E (cyclinD1, A, and E) in PCa cells [34,51,54,56], which seems to be partly due to Tanshinone’s ability to directly inhibit the phosphorylation of the pro-proliferative signaling pathway STAT3Tyr705 in PCa cells [51].