SQLE and posterior cortical atrophy: Existing publications show that the expression of some genes related to steroid and cholesterol biosynthesis in PCa cells treated with Tanshinone (mainly Tanshinone IIA) is significantly reduced [91], including methylsterol monooxygenase 1 (MSMO1/SC4MOL), squalene monooxygenase (SQLE), ATP-binding box subfamily G member 1 (ABCG1) and preprotein invertase subtilin kexin9 (PCSK9s).