PTGS2 and posterior cortical atrophy: It is noteworthy that Tanshinone can inhibit the activity of COX2 and play a significant inhibitory role in the transcription and expression of COX2 by acting similarly to non-steroidal anti-inflammatory drugs [108,109,110], while the prostaglandins generated by COX2-mediated production not only have a direct nourishing effect on PCa cells [111].