SKP2 and posterior cortical atrophy: In the experiment of WuCY et al., Tanshinone inhibits the translocation of phosphorylated STAT3 and protein expression of P-STAT3 and Skp2 in PCa cells in a dose-dependent manner, resulting in inhibition of the translation and transcription of RhoA and SNAI1 genes in PCa cells, which results in reduced invasiveness of PCa cells [35].