Prawan et al. [13] revealed that several pro-inflammatory mediators and cytokines (iNOS, COX-2, IL-1β, IL-6, and TNF-α) were reduced by ITCs and were related to the downregulation of NF-kappaB signaling pathways in HT-29-N9 human colon cancer cells. Here, TNF is linked to malignant colon neoplasm.