For example, the downregulation of fragments of CTSC, agrin, ARSA and GFAP was observed in patients with upper gastrointestinal tract cancer and myosteatotic vs. non-myosteatotic [44], whilst downregulation of annexin A1 and COL15A1 chain was observed in patients with a mixture of cancers and with leg-power measurement-based dynapenia [42]. The gene discussed is AGRN; the disease is cancer.