Chan et al. (2018), in a murine model with liver injury produced by the American Lifestyle-Induced Obesity Syndrome diet (ALIOS), demonstrated that the coadminstration of NDGA reduced body and epididymal fat weight and levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and triglycerides in the liver. The gene discussed is GPT; the disease is Syndromic obesity.