In AGC1-1, abnormal liver function tests just before the introduction of cKD (gamma-glutamyl-transferase (gGT) 694 (< 23 U/L), alanine amino transferase (ALT) 88 (< 28 U/L), aspartate amino transferase (AST) 47 (< 50 U/L) normalised within six months. This evidence concerns the gene GOT1 and chronic kidney disease.