APP and cancer: Most of the studies were conducted on mice (n = 38); strains included C57BL/6 (n = 18) [29,30,32,33,34,35,36,41,45,46,49,51,54,55,59,60,66,67], BALB/c (n = 3) [28,56,68], institute of cancer research (ICR) (n = 2) [37,38], APP/PS1 (n = 2) [43,48], DBA/2J [31], ape-/- [61], BALB/cJInv [44], Nrf2-/- [33], AhR-/- [33], IL10-/- [42], 3xTgAD [48], FUNDC1f/f [50], FUNDC1CKO [50], 10ScSn [53], 10ScSn-DmdmdxJ [53], mdx/Utr-/- (n = 1) [53], and unknown (n = 1) [61].