Immunofluorescent staining, Western blot and qPCR results confirmed the reversion of the EMT phenotype, i.e., the mesenchymal markers (N-Cad and Vim), and the EMT related transcription factors (Snail and Slug) were downregulated, while the epithelial markers (E-Cad and claudin) were upregulated, and the down-expression of β-catenin in the TNBC cells and mice tumor tissues was observed. The gene discussed is CDH1; the disease is neoplasm.