MAPK1 and migraine disorder: The findings showed that ALHP exerts a potential role in treating migraines by regulating multiple target genes, including ACE, SLC6A3, NR3C1, HTR2A, HTR2C, GRIN1, GRIN2A, DRD2, MAPK1, IL1B, RELA, NOS2, and PIK3CA.