Multivariate logistic regression analysis indicated that LAD (OR: 1.153, 95% CI: 1.056–1.259, p = 0.002), Scr (OR: 1.036, 95% CI: 1.009–1.063, p = 0.008), RDW-CV (OR: 2.033, 95% CI: 1.091–3.788, p = 0.026) and MnSOD (OR: 1.003, 95% CI: 1.001–1.005, p = 0.002) were independent risk factors for paroxysmal AF (Table 3). The gene discussed is SOD2; the disease is Paroxysmal atrial fibrillation.