COMP and juvenile idiopathic arthritis: On the other hand, analysis of correlations between COMP levels and ADAMTS5 levels in the blood of patients with JIA revealed significant correlations between the above-mentioned variables in patients before biological therapy (r = 0.348, p = 0.032), 6th (r = 0.646, p < 0.001), and 12th (r = 0.366, p = 0.024) month of therapy.