When analysing the literature, several risk factors for a prolonged length of stay have been identified: in the 2007 American-College-of-Surgeons-National-Surgical-Quality-Improvement-Program (ACS-NSQIP) [13], factors such as male gender, congestive heart failure, weight loss, Crohn’s disease, preoperative albumin <3.5 g/dL and hematocrit <47%, baseline sepsis, ASA class ≥ 3, open surgery, surgical time ≥190 min, were highlighted. This evidence concerns the gene ALB and congestive heart failure.