In our study, 5.8% (3/52) of PSMA-positive PET lesions, based on all patients with PSMA-positive findings, in the 18F-PSMA cohort and 11.4% (4/35) in the 68Ga-PSMA cohort were categorized as low-risk PC (GS < 7) with ISUP grade group 1. The gene discussed is FOLH1; the disease is pachyonychia congenita.