Intermediate-risk PC (GS 7) with ISUP grade groups 2 and 3 occurred in 40.4% (21/52) of 18F-PSMA-positive and in 60% (21/35) of 68Ga-PSMA-positive patients, whereas 53.8% (28/52, 18F-PSMA) and 28.6% (10/35, 68Ga-PSMA) showed high-risk PC lesions with an ISUP grade group 4 to 5 (Table 2, Figure 1 and Figure 2). The gene discussed is FOLH1; the disease is pachyonychia congenita.