HSPB1 and schizophrenia: Furthermore, according to a recent systematic review, copy number variant (CNV)-based studies have identified five schizophrenia-associated CNV regions containing genes that were found to be differentially expressed in schizophrenia (i.e., PPP1R2 in 3q29, HSPB1 in 7q11.23, INO80E and YPEL3 in 16p11.2, DHRS11 in 17q12, and SEPT5, RTN4R, and SLC2A11 in 22q11.2) [121].