In our previous study among patients who were treated at City of Hope Comprehensive Cancer Center (COH) in California (CA), patients living in areas with higher PM2.5 exposure had 1.66 (95% CI: 1.02–2.72) increased odds of TP53-mutated non-small cell lung cancer (NSCLC) [27]. This evidence concerns the gene TP53 and non-small cell lung carcinoma.