F10 and congenital factor VII deficiency: Congenital factor VII deficiency is characterized by a decreased amount of the total FVII and a very low level of circulating FVIIa, practically undetectable in standard tests.The gene coding for FVII is located on the long arm of chromosome 13, in the vicinity of two genes, related to vitamin K-dependent proteins/blood coagulation factors, factor X (FX), and PROZ (protein Z, vitamin K-dependent plasma glycoprotein) [3,4].