However, our previous assessment showed that β2M excretion of 100–299, 300–999 and ≥ 1000 μg/g creatinine were associated with 4.7-, 6.2- and 10.5-fold increases in the risk of an estimated glomerular filtration rate (eGFR) ≤ 60 mL/min/1.73 m2, which is commensurate with chronic kidney disease (CKD) [13]. Here, B2M is linked to chronic kidney disease.