Total LACTB is highly expressed in HL60 cells and low expressed in Raji cells;LACTB has multiple splicing isomers in leukemia cell lines, including XR1, V1, V2, and V3;The expression of V1 is high in U937 cells and low in Raji cells, that of V2 is high in HL60 cells and low in Raji cells, and V3 is poorly expressed in THP-1 cells. Here, LACTB is linked to leukemia.