Other DEGs that were upregulated in the PTX-res cells (Supplementary Table S1) included the β-tubulin encoding gene TUBB3, which has been associated with paclitaxel resistance [19] and FZD2, a member of the Wnt receptor Frizzled family, which has been shown to endow breast cancer cells with drug resistance [20]. Here, TUBB3 is linked to breast cancer.