For example, the accumulation of amyloid-β (Amyβ) is associated with Alzheimer’s disease (extracellular Aβ plaques), age-related macular degeneration (drusen), cardiomyopathy, and diabetes (islet amyloid aggregation) [17,18,19,20,21,22,23,24]. This evidence concerns the gene MYBL1 and early-onset autosomal dominant Alzheimer disease.