NPAS4 and memory impairment: RT-qPCR analysis in the same tissues confirmed the H-αSynOs-induced inhibition of Npas4 mRNA expression in the ACC (p = 0.0005; Unpaired Student’s t test) (Figure 3D) and in the hippocampus (p < 0.0001; Unpaired Student’s t test) (Figure 3E), indicating that the memory impairment was sustained by an altered neuronal activity in cognition-related areas.