While terms associated with tumour cell lines showed some degree of overlap between SMA types, these are likely unrelated to SMA, instead reflecting the high dominance of cancer-related studies constituting the protein–protein and protein–DNA interactions comprising the IPA® Knowledge Base, especially since tumour-related terms were not among the most enriched terms when the SMA comparisons were analysed in isolation (Figure 2B). This evidence concerns the gene SMN1 and cancer.