Notably, recent studies have demonstrated that microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) involve the post-transcriptional regulation of autophagy-related proteins and the development of epilepsy pathophysiologies, such as miR-101, miR-181b, miR-134, miR-142, miR-421, miR-223, and Zinc finger antisense 1 (ZFAS1), metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), respectively [270,271,272,273,274,275]. The gene discussed is MALAT1; the disease is epilepsy.