Similarly, in a study based on cyclophosphamide-induced immunosuppression model, rats fed diet with garlic extract showed an improvement in anti-infection immunity, since the contents of pro-inflammatory cytokines (TNF-α and IL-1β) were declined and anti-inflammatory cytokines (IL-12 and INF-γ) levels were elevated in the serum [34]. This evidence concerns the gene IL1B and infection.