The IE group exhibited an increased SOD activity (p < 0.05) and T-AOC level (p < 0.05) compared with the IC group; EGF supplementation tended to increase the GSH-Px activity (p = 0.053) and CAT activity (p = 0.072) and tended to decrease the MDA level (p = 0.090) in the jejunum of IUGR piglets compared with IUGR piglets without EGF supplementation. Here, EGF is linked to fetal growth restriction.