Importantly, this time of interaction of tumor cells with IL4rα−/− macrophages, whilst longer than initial intravascular interactions, was significantly shorter than in WT mice, with an average of 84.13 ± 12 min (n = 43, p < 0.0001) (Figure 3C,F; Supplemental Video S3). The gene discussed is IL4R; the disease is neoplasm.