CD8A and neoplasm: Meng Qiao et al. carried out IHC on the tumor tissues of liver metastasis–NSCLC patients, and IHC revealed that liver metastasis–NSCLC patients had a lower percentage of PD-L1+CD8+ ICs in comparison to non-liver metastasis patients (0 vs. 30.8%, p = 0.088) [13].