AXL and acute myeloid leukemia: Among the AXL inhibitors [83,84], the small molecule BGB324 (R428) was shown to increase the in vitro sensitivity of AML cells to Doxorubicin and Cytarabine [85], and is currently under evaluation in a multicenter phase Ib/II clinical trial alone or in combination with Cytarabine/Decitabine in high-risk myelodysplastic syndromes and R/R leukemia (NCT02488408).