KRAS and cancer: Based on the collective knowledgebase described above, as well as biologic evidence describing a signaling pathway interconnecting KRAS and its downstream effectors with TP53, we queried all 13 KRAS/TP53 pathway genes (including EGFR, KRAS, NF2, BRAF, PIK3CA, RASSF1, MAP2K1, AKT1, STK3, MAPK1, LATS1, MDM2, TP53) in The Cancer Genome Atlas (TCGA) pan-cancer MPM dataset [4,35] (available at https://www.cbioportal.org/ (accessed on 3 March 2022) using permanent link https://bit.ly/3BypsnC (accessed on 3 March 2022), with n = 82 patients).