CD4 and lip and oral cavity carcinoma: We have previously reported on the CD20 cluster score, i.e., a metric that combines the number of CD20 B cells within 20 μm of CD20 B cells (CD20 within CD20) and the number of CD20 B cells within 20 μm of CD4 T cells (CD20 within CD4), which correlated with the overall survival of patients with early oral cancer [18] (Figure 1A,B).