HLA-A and classic Hodgkin lymphoma: While only a small fraction of people infected with EBV will develop EBV-positive cHL [34], susceptibility is associated with variation in the human leukocyte antigen (HLA) region [35,36,37]; those with HLA-A*01 have an increased risk, and those with HLA-A*02 have a decreased risk [36,38,39].