In PGCCs, the evaluation of metabolic reprogramming revealed the presence of PLIN4, a perilipin covering the lipid droplets especially in chemo-resistant tumors [13]; the Warburg effect [35] and the involvement of the glycolytic pathway were also found to be induced in cancer environments and upon HCMV infection [12]. The gene discussed is PLIN4; the disease is cytomegalovirus infection.