ITGAX and neoplasm: In mouse PDAC, we observed that the proportion of total myeloid cells (CD11b+) within the population of CD45+ cells decreased in N6L-treated tumour-bearing mice compared to control mice (Figure 2A), whereas macrophages (CD11b+/F480+) and the frequency of M1 (CD11b+F4/80+MRC-CD11c+) and M2 (CD11b+F4/80+MRC+CD11c−) polarized macrophages were not (Figure 2B).