CD8A and neoplasm: The density of the CD3+ and CD8+ TILs, which was heterogeneous among patients, was slightly higher in the IChigh than the IClow subgroup, both inside the tumor and in the peritumoral stroma (Figure 4B, medians: 1.3% vs. 0.8% CD3+ TILs and 0.8% vs. 0.5% CD8+ TILs, and 7.6% vs. 6.4% CD3+ cells and 2.9% vs. 2.2% CD8+ cells in the stroma in the IChigh vs. IClow subgroups, respectively).