This result concerning PD-L1 is in line with previous reports [22,38] but not with others depicting high PD-L1 immunostaining in the tumor cells of CRC and, surprisingly, very weak expression using flow cytometry [19], reinforcing the importance of the standardization of immunohistochemistry among investigators (the PD-L1 antibody used, large tissue sections, a scoring system, etc.). The gene discussed is CD274; the disease is neoplasm.