MYCN and acute lymphoblastic leukemia: Spearman correlation analyses between UHRF1 mRNA levels and the gene expression of MYC family members (MYC, MYCN, and MYCL1), as well as CDK4 and CDK6 in the Haferlach and Gu leukemia datasets [29,30], indicated positive associations between UHRF1 and c-Myc, CDK4, and CDK6 in ALL (Figure 2C,D).