MMP9 and breast carcinoma: Bae et al. recently demonstrated that KCZ inhibits the proliferation and motility of MCF7 and MDA-MB-231 breast cancer cells via the induction of G1-phase arrest, and also observed reduced invasiveness through the inhibition of matrix metalloproteinase 9 (MMP9) in MDA-MB-231 but not MCF7 cells [34].