CD8A and neoplasm: On average, there were significantly more CD3+ and CD8+ T-cells located at the invasive margin (CD3: 1772 ± 1105, CD8: 769 ± 644 cells/mm2) than in the center of the tumor (CD3: 518 ± 570, CD8: 301 ± 445 cells/mm2, p ≤ 0.0001).