Since the Wnt/β-catenin pathway is considered to be a major regulator of the proliferation of colon cancer cells, and the AhR has been proposed to interfere with β-catenin-dependent signaling in colon cells [20], we also analyzed the levels of β-catenin in wild-type and AhR KO HCT116 cells. Here, AHR is linked to malignant colon neoplasm.