MUTYH and esophageal cancer: A heterozygous pathogenic missense variant in the MUTYH gene (NM_001128425.2:c.1187G > A p.(Gly396Asp), Table 2) was found in a patient with CRC who was diagnosed at age 39 (ID 142, Table 2) and had a familial history of CRC of paternal lineage and esophageal cancer of maternal lineage (Supplementary Table S2 and Figure S1).