Aside from the antigens expressed and secreted through the T1SS, T3SS, and T5SS systems in Salmonella enterica, other antigens have also been transported by this bacterium to APC or to the tumor microenvironment; these include survivin (a member of the inhibitor of apoptosis (IAP) protein family that promotes cellular proliferation and inhibits apoptosis), and proteins associated with tumor cell activation and migration [5,187]. Here, BIRC5 is linked to neoplasm.