Examples in which the T3SS has been used to transport TAA/TSA include studies in which Salmonella transports and secretes peptide 217–225 of Listeria monocytogenes protein 60 via the T3SS; its administration in a murine fibrosarcoma model induced an effector CD8+ T cell response, it decreased tumor size, and protected against challenge with an aggressively growing fibrosarcoma [33,132]. This evidence concerns the gene CD8A and neoplasm.