MMP9 and neoplasm: Stem cell genes (Nfatc4, IL33 and Cdkn1c, Aldh1a1, and Sox9), proteases/ECM genes (Mmp2, Mmp9, Mmp11, Mmp19, Col3a1, Col1a2, and Has1), angiocrine genes (Wnt, Fgf, Hgf, Vegfd, Vegfa, Pdgfc, and Tgfβ3), and Notch signalling (Notch3, Notch2, Rbpj, and Heyl) were upregulated in EVPs, compared to differentiated endothelial cells in the tumour [102] (Figure 2C).