GALNT14 promotes the O-glycosylation of death receptors 4/5 (DR4/5) [39] and mediates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in pancreatic carcinoma, non–small cell lung carcinoma, and melanoma cells [40]. This evidence concerns the gene TNFRSF10A and exocrine pancreatic carcinoma.