AFP and neoplasm: Among patients with tumor size > 3 cm, multivariate Cox analysis showed that serum AFP > 20 ng/mL (HR: 1.680, 95% CI: 1.233–2.290, p = 0.001) and ALBI grade 2–3 (HR: 1.725, 95% CI: 1.247–2.386, p = 0.001) were associated with decreased overall survival (Table 5).